All cells that are shipped will come with a post-thaw viability test. The number of passages one can expect any of the edited cells to grow is dependent on the gene that has been knocked out. If the gene knockout is lethal, we would expect to quickly lose the edited cells. If the gene knockout causes the cells to slow down, compared to their wildtype counterparts, we expect the cells to slowly drift towards wildtype and lose the edited cells. Finally, gene knockouts that will cause the cells to grow faster will eventually take over the population.
Articles in this section
- What is a Knockout Cell Pool?
- I can do the experiment myself. Why should I buy this?
- What do I get with this order of KO Cell Pools?
- What is a pool of KO cells?
- How do you select for the edited population?
- Do I need to design the guide RNA or target sequences?
- Is there any minimum or guaranteed editing efficiency for these cell pools?
- What are the conditions on the guarantee?
- Can you knockout non-coding genes?
- How do I get my cells to you?